Make your selection

List of substances for condition Group: Toxicity

All Human Animal Risk/Association ReviewRows: 604

Substance InfoDose WarnLink PubMed
Latest article
Curcumin 📋✍⛔38657456Curcumin alleviates zearalenone-induced liver injury in mice by scavenging reactive oxygen species and inhibiting mitochondrial apoptosis pathway
Melatonin 📋✍⛔38688425Melatonin prevents pulmonary fibrosis caused by PM2.5 exposure by targeting epithelial-mesenchymal transition
Vitamin C 📋✍⛔38597120Ascorbic acid attenuates gasoline-induced testicular toxicity, sperm quality deterioration, and testosterone imbalance in rats
Quercetin 📋✍⛔38726926The nephroprotective effect of Quercetin in Cyclophosphamide-induced renal toxicity might be associated with MAPK/ERK and NF-κB signal modulation activity
Resveratrol 📋✍⛔38672890Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway
Vitamin E 📋✍⛔38440903Ameliorative effects of zinc and vitamin E against phthalates-induced reproductive toxicity in male rats
N-Acetyl Cysteine 📋✍⛔38636261The use of amino acids and their derivates to mitigate against pesticide-induced toxicity
Selenium 📋✍⛔38633147Ameliorative effects of berberine and selenium against paracetamol-induced hepatic toxicity in rats
Lycopene 📋✍⛔38671900Lycopene as a Therapeutic Agent against Aflatoxin B1-Related Toxicity: Mechanistic Insights and Future Directions
Silymarin 📋✍⛔38700358Therapeutic Potential of Silymarin in Mitigating Paclitaxel-Induced Hepatotoxicity and Nephrotoxicity: Insights into Oxidative Stress, Inflammation, and Apoptosis in Rats
Hesperidin 📋✍⛔38700797Hesperidin neuroprotective effects against carbon monoxide-induced toxicity in male rats
Ginsenosides 📋✍⛔38708102Ameliorative effect of total ginsenosides from heat-treated fresh ginseng against cyclophosphamide-induced liver injury in mice
EGCG 📋✍⛔38687276Protective effects of EGCG on acrolein-induced Caenorhabditis elegans and its mechanism of life extension
Rutin 📋✍⛔38653908Rutin Attenuates Gentamycin-induced Hair Cell Injury in the Zebrafish Lateral Line via Suppressing STAT1
Nigella Sativa 📋✍⛔38379607Black seed oil reverses chronic antibiotic-mediated depression and social behaviour deficits via modulation of hypothalamic mitochondrial-dependent markers and insulin expression
Ginkgo Biloba 📋✍⛔38286926Ginkgo biloba extract protects against tartrazine-induced testicular toxicity in rats: involvement of antioxidant, anti-inflammatory, and anti-apoptotic mechanisms
Thymoquinone 📋 ⛔38658488The Effect of Thymoquinone on the TNF-α/OTULIN/NF-κB Axis Against Cisplatin-Ä°nduced Testicular Tissue Damage
Lipoic Acid 📋✍⛔38465655Dietary lipoic acid alleviates autism-like behavior induced by acrylamide in adolescent mice: the potential involvement of the gut-brain axis
Astaxanthin 📋✍⛔38720817Ameliorative impacts of astaxanthin against atrazine-induced renal toxicity through the modulation of ionic homeostasis and Nrf2 signaling pathways in mice
Grape Seed extract 📋✍⛔38500515Grape seed proanthocyanins protect fluoride-induced hepatotoxicity via the Nrf2 signaling pathway in male rats
Moringa Oleifera 📋✍⛔38455639Moringa oleifera leaves ethanolic extract counteracts cortical neurodegeneration induced by aluminum chloride in rats
Berberine 📋✍⛔38633147Ameliorative effects of berberine and selenium against paracetamol-induced hepatic toxicity in rats
CoQ10 📋✍⛔38716935Protective effect of coenzyme Q10 in cyclophosphamide-induced kidney damage in rats
Zinc 📋✍⛔38629506Zinc ameliorates acrylamide-induced oxidative stress and apoptosis in testicular cells via Nrf2/HO-1/NfkB and Bax/Bcl2 signaling pathway
Ellagic Acid 📋✍⛔38338554Evaluation of the Potential Protective Effect of Ellagic Acid against Heavy Metal (Cadmium, Mercury, and Lead) Toxicity in SH-SY5Y Neuroblastoma Cells
Apigenin 📋✍⛔38718656Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43
Gallic Acid 📋 ⛔38474465Neuroprotective Effects of Polysaccharides and Gallic Acid from Amauroderma rugosum against 6-OHDA-Induced Toxicity in SH-SY5Y Cells
Ginseng 📋✍⛔38554338Protective effects of Panax Ginseng against 131I-induced genotoxicity in patients with differentiated thyroid cancer
Spirulina 📋✍⛔38072319Spirulina platensis ameliorates hepatic oxidative stress and DNA damage induced by aflatoxin B1 in rats
Vitamin D3 📋✍⛔38624052Electrocardiographic, biochemical, and scintigraphic evidence for the cardioprotective effect of paricalcitol and vitamin D3 on doxorubicin-induced acute cardiotoxicity in rats
Luteolin 📋✍⛔38565590Neuroprotective mechanisms of luteolin in glutamate-induced oxidative stress and autophagy-mediated neuronal cell death
Crocin 📋✍⛔38662441Crocin, the compound of the dried stigma of Crocus sativus L (saffron), restores doxorubicin-induced disturbances in kidney functioning, oxidative stress, inflammation, renal tissue morphology and TGF-β signalling pathways
Sulforaphane 📋✍⛔37906532Sulforaphane ameliorate Arsenic induced cardiotoxicity in rats: Role of PI3k/Akt mediated Nrf2 signaling pathway
Chrysin 📋✍⛔38432408Targeting SIRT1, NLRP3 inflammasome, and Nrf2 signaling with chrysin alleviates the iron-triggered hepatotoxicity in rats
Naringenin 📋✍⛔38647073Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1
Puerarin 📋✍⛔38287862Puerarin Attenuates Cycloheximide-Induced Oxidative Damage and Memory-Consolidation Impairment in Rats
Metformin 📋✍⛔38487671Metformin Inhibits Autophagy, Mitophagy and Antagonizes Doxorubicin-Induced Cardiomyocyte Death
Goji Berry 📋✍⛔38543108Anthocyanins from Lycium ruthenicum Murray Mitigate Cadmium-Induced Oxidative Stress and Testicular Toxicity by Activating the Keap1/Nrf2 Signaling Pathway
Naringin 📋✍⛔38419883Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology
Salidroside 📋 38727159Salidroside Ameliorates Lung Injury Induced by PM 2.5by Regulating SIRT1-PGC-1α in Mice
Carvacrol 📋✍⛔38302077Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve
Allicin 📋✍⛔37830900Allicin Alleviates Mitochondrial Dysfunction in Acrylamide-Induced Rat Kidney Involving the Regulation of SIRT1
L-Carnitine 📋✍⛔38497852Ameliorative effects of L-carnitine as an antioxidant against testicular toxicity induced by AlCl3 in male albino rats
Taurine 📋✍⛔38693965Adverse hematological profiles associated with chlorpromazine antipsychotic treatment in male rats: Preventive and reversal mechanisms of taurine and coenzyme-Q10
Astragalosides 📋✍⛔38521426Astragaloside IV ameliorates cisplatin-induced liver injury by modulating ferroptosis-dependent pathways
Diosmin 📋✍⛔38072527Nephroprotective effect of diosmin against sodium arsenite-induced renal toxicity is mediated via attenuation of oxidative stress and inflammation in mice
Acetyl-L-Carnitine 📋✍⛔37511276Acetyl-L-Carnitine and Liposomal Co-Enzyme Q10 Attenuate Hepatic Inflammation, Apoptosis, and Fibrosis Induced by Propionic Acid
Ollive Leaf extract 📋✍⛔38722494Simultaneous Exposure to Noise and Toluene Induces Oxidative and Inflammatory Damage in the Heart of Wistar Rats: Therapeutic Potential of Olea europaea L. Leaf Extract
Dihydroquercetin 📋 38465425Neuroprotective effect of taxifolin against aluminum chloride-induced dementia and pathological alterations in the brain of rats: Possible involvement of toll-like receptor 4
Fisetin 📋✍⛔38708470Fisetin ameliorates methotrexate induced liver fibrosis
Bee Propolis 📋✍⛔38595651Ameliorative impacts of propolis against testicular toxicity promoted by doxorubicin
Omega-3 Fatty Acids 📋✍⛔38585532Evaluating the renoprotective effects of omega-3-6-9 against cisplatin-induced nephrotoxicity in mice
Green Tea Polyphenols 📋✍⛔38470815Green tea polyphenols inhibit TBBPA-induced lung injury via enhancing antioxidant capacity and modulating the NF-κB pathway in mice
Vitamin B9 📋✍⛔37409447Toxicity of methomyl insecticides to testicular cells and protective effect of folic acid
Hesperetin 📋 38056121Hesperetin protects hippocampal neurons from the neurotoxicity of Aflatoxin B1 in mice
Kaempferol 📋✍⛔38387328Kaempferol alleviates bisphenol A reproductive toxicity in rats in a dose-dependent manner
Fucoidan 📋✍⛔37844814Fucoidan may treat jellyfish dermatitis by inhibiting the inflammatory effect of jellyfish venom
Garlic 📋✍⛔38458692A combination of silymarin and garlic extract enhances thyroid hormone activation and body metabolism in orally intoxicated male rats with atrazine: Impact on hepatic iodothyronine deiodinase type 1
Rosmarinic Acid 📋✍ 38631488Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway
Gingerol 📋✍ 38157955Mercury chloride causes cognitive impairment, oxidative stress and neuroinflammation in male Wistar rats: The potential protective effect of 6-gingerol-rich fraction of Zingiber officinale via regulation of antioxidant defence system and reversal of pro-inflammatory markers increase
Licorice Root 📋✍⛔36842722The attenuation effect of licorice on the hepatotoxicity of Euodiae Fructus by inhibiting the formation of protein conjugates and GSH depletion
Date 📋 ⛔38529813Water-soluble phenolics from Phoenix dactylifera fruits as potential reno-protective agent against cisplatin-induced toxicity: pre- and post-treatment strategies
Myricetin 📋 ⛔38051478Protective Role of Myricetin and Fisetin Against Nephrotoxicity Caused by Lead Acetate Exposure through Up-regulation of Nrf2/HO-1 Signalling Pathway
Silibinin 📋✍ 38675395Silibinin's Effects against Methotrexate-Induced Hepatotoxicity in Adjuvant-Induced Arthritis Rat Model
Ginger 📋✍⛔38338475Ameliorative Effects of Zingiber officinale Rosc on Antibiotic-Associated Diarrhea and Improvement in Intestinal Function
Ashwagandha 📋✍⛔37663806Protective impacts of Withania somnifera leaf extract from Taif area against diclofenac induced hepato-renal toxicity: role of antioxidants, inflammation, apoptosis, and anti-oxidative stress biomarkers
Chokeberry 📋✍⛔38398826The Protective Impact of Aronia melanocarpa L. Berries Extract against Prooxidative Cadmium Action in the Brain-A Study in an In Vivo Model of Current Environmental Human Exposure to This Harmful Element
NMN 📋✍⛔38564869Nicotinamide mononucleotide maintains cytoskeletal stability and fortifies mitochondrial function to mitigate oocyte damage induced by Triocresyl phosphate
Pomegranate 📋 ⛔38303124Hepatoprotective effect of methanol fruit extract of Punica granatum L in highly active antiretroviral therapy-induced toxicity in Wistar rats
Royal Jelly 📋✍⛔38500210Cardioprotective role of royal jelly in the prevention of celecoxib-mediated cardiotoxicity in adult male albino rats
Chlorella 📋✍⛔38722343Nicotine exacerbates liver damage in a mice model of Ehrlich ascites carcinoma through shifting SOD/NF-κB/caspase-3 pathways: ameliorating role of Chlorella vulgaris
Reishi Mushrooms 📋✍⛔37841924Therapeutic potential of Ganoderma lucidum polysaccharide peptide in Doxorubicin-induced nephropathy: modulation of renin-angiotensin system and proteinuria
Vitamin B12 📋✍⛔38645491Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats
Chlorogenic Acid 📋✍⛔38136147Chlorogenic Acid Alleviated AFB1-Induced Hepatotoxicity by Regulating Mitochondrial Function, Activating Nrf2/HO-1, and Inhibiting Noncanonical NF-κB Signaling Pathway
Pomegranate Peel extract 📋✍⛔38670510Mitigating effect of pomegranate peel extract against the furan induced testicular injury by apoptosis, steroidogenic enzymes and oxidative stress
TUDCA 📋✍⛔33631298Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum
Dandelion 📋✍⛔36210509Protective role of the dandelion extract against the blood-liver axis, cell membranes, and anemia disorder in sodium benzoate-exposed rats
Ferulic Acid 📋✍⛔37966574Mitigating effect of ferulic acid on di-(2-ethylhexyl) phthalate-induced neurocognitive dysfunction in male rats with a comprehensive in silico survey
Olive Oil 📋✍⛔37673343The potential protectivity of honey and olive oil in methotrexate induced renal damage in rats
Baicalin 📋✍⛔38663526Baicalin restore intestinal damage after early-life antibiotic therapy: the role of the MAPK signaling pathway
Cannabidiol 📋✍⛔38401722Evaluation of the effect of cannabidiol on the THLE-2 liver cell line exposed to lead
Carnosic Acid 📋 38538219Brain Mitochondria as a Therapeutic Target for Carnosic Acid
Genistein 📋✍⛔38244450Genistein prevents the production of hypospadias induced by Di-(2-ethylhexyl) phthalate through androgen signaling and antioxidant response in rats
Ginger extract 📋✍⛔37174437Protective Effect of Quercetin and Ginger ( Zingiber officinale) Extract against Dimethoate Potentiated Fluoride-Induced Nephrotoxicity in Rats
Aged Garlic 📋✍⛔36856009Aged Garlic Extract Prevents Alcohol-Induced Cytotoxicity through Induction of Aldehyde Dehydrogenase 2 in the Liver of Mice
Andrographis 📋✍⛔38057817Ethanol extract of Andrographis paniculata alleviates aluminum-induced neurotoxicity and cognitive impairment through regulating the p62-keap1-Nrf2 pathway
Coconut Oil 📋 ⛔38629097Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway
Indian Gooseberry 📋 ⛔38030098Aqueous leaf extract of Phyllanthus amarus protects against oxidative stress and misfiring of dopaminergic neurons in Paraquat-induced Parkinson's disease-like model of adult Wistar rats
Oleuropein 📋 38582273Oleuropein attenuates the nephrotoxic effect of sunitinib in rats: Unraveling the potential role of SIRT6/Notch-1/NLRP-3/IL-1β axis
Pine Bark 📋✍⛔38465002The effects of Pycnogenol, a pine bark extract on pulmonary inflammation by Asian sand dust in mice
Dihydromyricetin 📋✍⛔38035992Dihydromyricetin protects against gentamicin-induced nephrotoxicity via upregulation of renal SIRT3 and PAX2
Mangiferin 📋 ⛔37455591C-Glucosyl Xanthone derivative Mangiferin downregulates the JNK3 mediated caspase activation in Almal induced neurotoxicity in differentiated SHSY-5Y neuroblastoma cells
Papaya 📋✍⛔37944220Antioxidant activity of Carica papaya & Persea americana fruits against cadmium induced neurotoxicity, nephrotoxicity, and hepatotoxicity in rats with a computational approach
Piperine 📋✍⛔38528700Piperine mitigates oxidative stress, inflammation, and apoptosis in the testicular damage induced by cyclophosphamide in mice
Pterostilbene 📋✍⛔37566321Protective potential of pterostilbene against cyclophosphamide-induced nephrotoxicity and cystitis in rats
Saffron 📋✍⛔37827264The effects of Crocus sativus extract on inhaled paraquat-induced lung inflammation, oxidative stress, pathological changes and tracheal responsiveness in rats
Zingerone 📋 38629098Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways
Aloe Vera 📋✍⛔38467965Aloe vera gel relieves cadmium triggered hepatic injury via antioxidative, anti-inflammatory, and anti-apoptotic routes
Astragalus Root 📋✍⛔38479258Astragalus polysaccharides attenuate chemotherapy-induced immune injury by modulating gut microbiota and polyunsaturated fatty acid metabolism
Fenugreek 📋✍⛔37554151Fenugreek seed powder protects mice against arsenic-induced neurobehavioral changes
Schisandra 📋✍⛔35588406Schisandra chinensis essential oil attenuates acetaminophen-induced liver injury through alleviating oxidative stress and activating autophagy
Tannic Acid 📋✍⛔38455638Tannic acid ameliorates the hazards effect of beryllium induced neuro-alterations and oxidative stress in adult male rats
Tribulus Terrestris 📋✍⛔35605919Ameliorative effect of methanolic extract of Tribulus terrestris L. on nicotine and lead-induced degeneration of sperm quality in male rats
Andrographolide 📋 38400848An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity
Boric Acid 📋✍⛔38393193Boron Compounds Mitigate 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity in Human Peripheral Blood Mononuclear Cells
Eugenol 📋 38592566Cardioprotective Effect of Eugenol Against Cd-Induced Inflammation, Oxidative Stress, and Dyslipidemia in Male Rats: An In Vivo and Molecular Docking Study
Fig 📋 ⛔35874505Ameliorative or corrective effects of Fig " Ficus carica" extract on nickel-induced hepatotoxicity in Wistar rats
Icariin 📋✍ 38226245Icariin prevents methylmercury-induced experimental neurotoxicity: Evidence from cerebrospinal fluid, blood plasma, brain samples, and in-silico investigations
Magnesium 📋✍⛔38056458Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism
Galangin 📋 37655750Galangin attenuates doxorubicin-induced cardiotoxicity via activating nuclear factor erythroid 2-related factor 2/heme oxygenase 1 signaling pathway to suppress oxidative stress and inflammation
Green Tea 📋✍⛔38229977Amelioration of nonylphenol-induced anxiety/depression-like behaviors in male rats using green tea and Zn-Se tea interventions
Morin 📋 38027731Acute aflatoxin B1-induced hepatic and cardiac oxidative damage in rats: Ameliorative effects of morin
Sea Buckthorn 📋✍⛔36557990Protective Effects of Hippophae rhamnoides L. Phenylpropanoids on Doxorubicin-Induced Cardiotoxicity in Zebrafish
Turmeric 📋✍⛔38027700The neuroprotective potential of turmeric rhizome and bitter melon on aspartame-induced spatial memory impairment in rats
Wormwood 📋✍⛔38162595Protective impacts of Artemisia annua against hepatic toxicity induced by gentamicin
Barberry 📋✍⛔36910359Berberis lyceum root bark extract attenuates anticancer drugs induced neurotoxicity and cardiotoxicity in rats
Glycyrrhizic Acid 📋✍⛔38725079Glycyrrhizic acid inhibits DNA damage repair and enhances cisplatin-induced apoptosis of melanoma cells
Grape 📋 ⛔37112618Protective Effects of a Red Grape Juice Extract against Bisphenol A-Induced Toxicity in Human Umbilical Vein Endothelial Cells
Lutein 📋✍⛔38314281Possible mechanisms involved in the protective effect of lutein against cyclosporine-induced testicular damage in rats
Nobiletin 📋✍ 38570541Nobiletin alleviates cisplatin-induced ototoxicity via activating autophagy and inhibiting NRF2/GPX4-mediated ferroptosis
Punicalagin 📋✍⛔36293191Punicalagin Protects against the Development of Methotrexate-Induced Hepatotoxicity in Mice via Activating Nrf2 Signaling and Decreasing Oxidative Stress, Inflammation, and Cell Death
Baicalein 📋✍⛔37354967Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation
Betulinic Acid 📋 38395262Betulinic acid attenuates T-2 toxin-induced lung injury by activating Nrf2 signaling pathway and inhibiting MAPK/NF-κB signaling pathway
Cinnamon 📋✍⛔36911850Analyzing cross-talk of EPO and EGF genes along with evaluating therapeutic potential of Cinnamomum verum in cigarette-smoke-induced lung pathophysiology in rat model
Linalool 📋 ⛔38657337Therapeutic potential of the linalool against cadmium-induced testicular tissue damage
Thymol 📋✍⛔37648049Thymol abates the detrimental impacts of imidacloprid on rat brains by lessening oxidative damage and apoptotic and inflammatory reactions
Angelica 📋✍⛔38211994[Protective effect and mechanism of Astragalus membranaceus and Angelica sinensis compatibility against triptolide-induced hepatotoxicity by regulating Keap1/Nrf2/PGC-1α]
Beets 📋✍⛔37483802Beet leaf (beta vulgaris L.) extract attenuates iron-induced testicular toxicity: Experimental and computational approach
Caffeic Acid 📋✍⛔38591965Caffeic acid attenuates memory dysfunction and restores the altered activity of cholinergic, monoaminergic and purinergic in brain of cadmium chloride exposure rats
Honokiol 📋 38364735Beneficial effect of honokiol and magnolol on polyol pathway and oxidative stress parameters in the testes of diabetic rats
L-Glutamine 📋✍⛔38154151Glutamine attenuates bisphenol A-induced intestinal inflammation by regulating gut microbiota and TLR4-p38/MAPK-NF-κB pathway in piglets
Mangosteen 📋✍⛔36445559Alpha-mangostin Protects PC12 Cells Against Neurotoxicity Induced by Cadmium and Arsenic
Mulberry 📋 ⛔36514774Mulberry leaves juice attenuates arsenic-induced neurobehavioral and hepatic disorders in mice
Walnut 📋 ⛔36279514Hepatoprotective effects of walnut oil and Caralluma tuberculata against paracetamol in experimentally induced liver toxicity in mice
Asiatic Acid 📋 37413899Asiatic acid alleviates cisplatin-induced renal fibrosis in tumor-bearing mice by improving the TFEB-mediated autophagy-lysosome pathway
Black Tea 📋✍⛔36061029Prevention of inorganic arsenic induced squamous cell carcinoma of the skin in Swiss albino mice by black tea through epigenetic modulation
Docosahexaenoic Acid 📋✍⛔38459987Protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal PM2.5 exposure in young rats
Echinacea 📋✍⛔38467789Immuno-antioxidative reno-modulatory effectiveness of Echinacea purpurea extract against bifenthrin-induced renal poisoning
Formononetin 📋 38192850Formononetin ameliorates cisplatin-induced hair cell death via activation of the PI3K/AKT-Nrf2 signaling pathway
Fucoxanthin 📋✍⛔37999416Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats
Gotu Kola 📋✍⛔38580733Centella asiatica mitigates the detrimental effects of Bisphenol-A (BPA) on pancreatic islets
Graviola 📋✍⛔38362149Annona Muricata L. extract restores renal function, oxidative stress, immunohistochemical structure, and gene expression of TNF-α, IL-β1, and CYP2E1 in the kidney of DMBA-intoxicated rats
Hydroxytyrosol 📋 37699441Modulation of mi-RNA25/Ox-LDL/NOX4 signaling pathway by polyphenolic compound Hydroxytyrosol as a new avenue to alleviate cisplatin-induced acute kidney injury, a mechanistic study in rats
Hyperoside 📋 38500281Neuroinflammatory Response and Redox-regulation Activity of Hyperoside in Manganese-induced Neurotoxicity Model of Wistar Rats
Pomegranate Seed extract 📋 ⛔35782771Pomegranate seed oil protects against tacrolimus-induced toxicity in the heart and kidney by modulation of oxidative stress in rats
Schisandrins 📋 37111128Prevention of the Pro-Aggressive Effects of Ethanol-Intoxicated Mice by Schisandrin B
Stinging Nettle 📋✍⛔38017656Protective effects of Urtica dioica on the cerebral cortex damage induced by Potassium bromate in adult male albino rats
Tangeretin 📋 37933488Dietary tangeretin improved antibiotic-associated diarrhea in mice by enhancing the intestinal barrier function, regulating the gut microbiota, and metabolic homeostasis
Anthocyanins 📋✍⛔35513806Impact of anthocyanin on genetic stability in mammary adenocarcinoma-induced mice treated with methotrexate
Betaine 📋✍⛔38713257Modulation of the Nrf-2 and HO-1 signalling axis is associated with Betaine's abatement of fluoride-induced hepatorenal toxicities in rats
Blueberry 📋✍⛔38621470Anthocyanins from blueberry ameliorated arsenic-induced memory impairment, oxidative stress, and mitochondrial-biosynthesis imbalance in rat hippocampal neurons
Boswellic Acid 📋✍⛔38718656Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43
Burdock 📋 ⛔32562918Isolation, structure elucidation and neuroprotective effects of caffeoylquinic acid derivatives from the roots of Arctium lappa L
Cinnamon Essential Oil 📋✍⛔37375915Cinnamon Oil Alleviates Acetaminophen-Induced Uterine Toxicity in Rats by Abrogation of Oxidative Stress, Apoptosis, and Inflammation
Fish Oil 📋✍⛔38486044Fish oil ameliorates ethanol-induced gastric injury in rat by modulating gene related to apoptosis
Paeoniflorin 📋 38705442Paeoniflorin attenuates particulate matter-induced acute lung injury by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis through activation of the Nrf2 signaling pathway
Phytochemicals 📋 37440795Environmental toxicants and health adversities: A review on interventions of phytochemicals
Roselle 📋✍⛔37450997Hibiscus-cisplatin combination treatment decreases liver toxicity in rats while increasing toxicity in lung cancer cells via oxidative stress- apoptosis pathway
Apple 📋 ⛔35167638Apple phenolic extracts ameliorate lead-induced cognitive impairment and depression- and anxiety-like behavior in mice by abating oxidative stress, inflammation and apoptosis via the miR-22-3p/SIRT1 axis
Catechins 📋 35738327Catechins protect against acrylamide- and glycidamide-induced cellular toxicity via rescuing cellular apoptosis and DNA damage
Coriander 📋 ⛔36830010Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo
Isoliquiritigenin 📋 37807075Deep learning-assisted high-content screening identifies isoliquiritigenin as an inhibitor of DNA double-strand breaks for preventing doxorubicin-induced cardiotoxicity
L-Arginine 📋✍⛔37660966Protective effects of L-arginine on Alzheimer's disease: Modulating hippocampal nitric oxide levels and memory deficits in aluminum chloride-induced rat model
Micronutrients 📋 ⛔38474096Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy
Onion 📋✍⛔38309514Investigating the therapeutic potential of Allium cepa extract in combating pesticide exposure induced ocular damage
Polydatin 📋✍ 37352982Protective effects of polydatin on ileum injury in mice exposed to aflatoxin B1
Tanshinone 📋 38035519Tanshinone IIA protects intestinal epithelial cells from deoxynivalenol-induced pyroptosis
Acai Berry 📋✍⛔38370884Comparing the effects of Cyperus esculentus hydroethanolic extract and Euterpe oleracea on reproductive efficacy against cadmium-induced testicular toxicity in male rats
Biochanin A 📋 36181478Mechanisms of Biochanin A Alleviating PM2.5 Organic Extracts-Induced EMT of A549 Cells through the PI3K/Akt Pathway
Caffeine 📋✍⛔38149470Preventive effects of caffeine on nicotine plus high-fat diet-induced hepatic steatosis and gain weight: A possible explanation for why obese smokers with high coffee consumption tend to be leaner
CAPE 📋 37786469Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium
Geraniol 📋 38362098The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway
Lactobacillus plantarum 📋 ⛔38101482Ameliorative potential of synbiotic combination of Lactobacillus sp. and polyphenols against Benzo[a]pyrene-induced toxicity in Caco-2 cell line
Nicotinamide Riboside 📋✍⛔38333051Comparison of protective effects of nicotinamide mononucleotide and nicotinamide riboside on DNA damage induced by cisplatin in HeLa cells
Procyanidins 📋 ⛔37515969Procyanidin B2 alleviates uterine toxicity induced by cadmium exposure in rats: The effect of oxidative stress, inflammation, and gut microbiota
Rosemary 📋✍⛔38392217Protective Potential of a Botanical-Based Supplement Ingredient against the Impact of Environmental Pollution on Cutaneous and Cardiopulmonary Systems: Preclinical Study
Wogonin 📋✍⛔37515497Wogonin alleviates BaP-induced DNA damage and oxidative stress in human airway epithelial cells by dual inhibiting CYP1A1 activity and expression
Argan Oil 📋✍⛔33843382Protective effect of argan oil on DNA damage in vivo and in vitro
Bay Leaf 📋 ⛔36590130Aqueous extract of bay leaf ( Laurus nobilis) ameliorates testicular toxicity induced by aluminum chloride in rats
Bromelain 📋✍⛔36462588Ameliorative effects of bromelain on aluminum-induced Alzheimer's disease in rats through modulation of TXNIP pathway
Butyrate 📋 ⛔38581912Protective effects of sodium butyrate on fluorosis in rats by regulating bone homeostasis and serum metabolism
Emodin 📋 ⛔38009195Emodin ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis through the remodeling of gut microbiota composition
Isorhamnetin 📋 38466121Isorhamnetin ameliorates cisplatin-induced acute kidney injury in mice by activating SLPI-mediated anti-inflammatory effect in macrophage
Medicinal Plants 📋 38356556Medicinal herbs and their metabolites with biological potential to protect and combat liver toxicity and its disorders: A review
Paeonol 📋 36358984Beneficial Effect of Paeonol on Antibiotic-Associated Inflammatory Response in Mice with Diarrhea
Salvianolic Acid 📋 38382651Salvianolic acid extract prevents Tripterygium wilfordii polyglycosides-induced acute liver injury by modulating bile acid metabolism
Scutellarin 📋 36419360Scutellarin Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Myocardial Fibrosis, Apoptosis and Autophagy in Rats
Sesamol 📋 37601053The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways
White Tea 📋 ⛔36290224Tannic Acid and Tea Prevents the Accumulation of Lead and Cadmium in the Lungs, Heart and Brain of Adolescent Male Wistar Rats-Possible Therapeutic Option
Amygdalin 📋✍⛔38529199Beneficial role of amygdalin extracts against animal growth regulator Boldjan induced cardiac toxicity, injury and oxidative stress in male rats
Cabbage 📋 ⛔38327044Protective effect of diindolylmethane-enriched dietary cabbage against doxorubicin-induced cardiotoxicity in mice
Carrot 📋 ⛔35947743Aquoeus Extracts of Daucus Carota (Linn) Protected the Postnatal Developing Cerebellum of Wistar Rats Against Arsenic-Induced Oxidative Stress
Clove 📋 ⛔37755735Mechanistic Assessment of Anise Seeds and Clove Buds against the Neurotoxicity Caused by Metronidazole in Rats: Possible Role of Antioxidants, Neurotransmitters, and Cytokines
Cocoa 📋✍⛔37324470Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice
Coffee 📋✍⛔38539875Evaluating the Neuroprotective Potential of Caffeinated Coffee in the Context of Aluminum-Induced Neurotoxicity: Insights from a PC12 Cell Culture Model
Essential Oils 📋 ⛔36928838Repellent Screening of Selected Plant Essential Oils Against Dengue Fever Mosquitoes Using Behavior Bioassays
Frankincense 📋✍⛔37866446Guided discovery of hepatoprotective polyhydroxy cembrane-type diterpenoids from the gum resin of Boswellia carterii by MS/MS molecular networking
Ginkgolides 📋 37715308Ginkgolide A downregulates transient receptor potential (melastatin) 2 to protect cisplatin-induced acute kidney injury in rats through the TWEAK/Fn14 pathway: Ginkgolide A improve acute renal injury
Lotus 📋 ⛔37368582Effects of Nelumbonucifera Gaertn. Petal Tea Extract on Hepatotoxicity and Oxidative Stress Induced by Mancozeb in Rat Model
Oregano 📋✍⛔33424252The impact of different extracts of six Lamiaceae species on deleterious effects of oxidative stress assessed in acellular, prokaryotic and eukaryotic models in vitro
Sesamin 📋✍ 38141790Sesamin mitigates lead-induced behavioral deficits in male rats: The role of oxidative stress
Basil 📋✍⛔38433659Sweet basil ( Ocimum basilicum) leaf and seed extracts alleviate neuronal dysfunction in aluminum chloride-induced neurotoxicity in Drosophila melanogaster Meigen model
Capsaicin 📋✍⛔37916995Capsaicin alleviates doxorubicin-induced acute myocardial injury by regulating iron homeostasis and PI3K-Akt signaling pathway
Cardamom 📋✍⛔37318456Protective effect of ethanolic extract of Elettaria Cardamomum against gentamicin hepato-renal toxicity in male albino rats
Coconut 📋 ⛔37975366Oral administration of naringenin and a mixture of coconut water and Arabic gum attenuate oxidative stress and lipid peroxidation in gentamicin-induced nephrotoxicity in rats
Coumaric acid 📋 38513920Molecular insights into the antioxidative and anti-inflammatory effects of P-coumaric acid against bisphenol A-induced testicular injury: In vivo and in silico studies
Daidzein 📋✍⛔38406792Neuroprotective effects of daidzein against ifosfamide-induced neurotoxicity in male rats: role of selected inflammatory and apoptotic markers
Holy Basil 📋✍⛔37860117Hepatoprotective effects of bioactive compounds from traditional herb Tulsi ( Ocimum sanctum Linn) against galactosamine-induced hepatotoxicity in rats
L-Carnosine 📋✍⛔37742605Carnosine alleviates cisplatin-induced acute kidney injury by targeting Caspase-1 regulated pyroptosis
L-Theanine 📋✍⛔38438008L-theanine attenuates H2O2-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway
Licochalcones 📋 38284775The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
Marjoram 📋 ⛔37273614Potential Mechanisms of Imidacloprid-Induced Neurotoxicity in Adult Rats with Attempts on Protection Using Origanum majorana L. Oil/Extract: In Vivo and In Silico Studies
Orange 📋 ⛔35004810Orange Juice Attenuates Circulating miR-150-5p, miR-25-3p, and miR-451a in Healthy Smokers: A Randomized Crossover Study
Sage 📋✍⛔38472741Sage (Salvia officinalis) alleviates trazadone induced rat cardiotoxicity mediated via modulation of autophagy and oxidative stress
Sesame Oil 📋 ⛔38548024The Protective Role of Sesame Oil against Parkinson's-Like Disease Induced by Manganese in Rats
Syringic Acid 📋 38430353The Protective Effects of Syringic Acid on Bisphenol A-Induced Neurotoxicity Possibly Through AMPK/PGC-1α/Fndc5 and CREB/BDNF Signaling Pathways
Artichoke 📋✍⛔38031637Protective effect of chicory and/or artichoke leaves extracts on carbon tetrachloride and gamma-irradiation-induced chronic nephrotoxicity in rats
Calycosin 📋 38576421Exploring the effects of calycosin on anthracycline-induced cardiotoxicity: a network pharmacology, molecular docking, and experimental study
Citicoline 📋✍⛔37105618Citicoline ameliorates arsenic-induced hepatotoxicity and diabetes in mice by overexpression of VAMP2, PPAR-γ, As3MT, and SIRT3
Cordyceps 📋✍⛔33030475Using Cordyceps militaris extracellular polysaccharides to prevent Pb 2+-induced liver and kidney toxicity by activating Nrf2 signals and modulating gut microbiota
Crocetin 📋 34697146Protective Effects of Crocetin on Arsenic Trioxide-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells
Galangal 📋✍⛔37757646Hepatoprotective effects of Alpinia officinarum rhizome extract on cisplatin-induced hepatotoxicity in rats: A biochemical, histopathological and immunohistochemical study
Haritaki 📋✍⛔35400254Cardio-protective effects of Terminalia catappa leaves and Terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy in rats
Lemongrass Essential Oil 📋✍⛔37749735Lemongrass Essential Oil Attenuates Perfluorooctane Sulfonate-Induced Jejunal Mucosal Injury in Rat: A Histological, Immunohistochemical, and Biochemical Study
Mango Leaf 📋 ⛔37674830Counteractive effects of extracts of Mangifera indica on testes of Wistar Rat exposed to cyclophosphamide
Nootkatone 📋 37755794Nootkatone Mitigated Melamine-Evoked Hepatotoxicity by Featuring Oxidative Stress and Inflammation Interconnected Mechanisms: In Vivo and In Silico Approaches
Phloretin 📋 37659297Phloretin alleviates doxorubicin-induced cardiotoxicity through regulating Hif3a transcription via targeting transcription factor Fos
Poria Mushrooms 📋✍ 36674937Poria cocos Polysaccharide Ameliorated Antibiotic-Associated Diarrhea in Mice via Regulating the Homeostasis of the Gut Microbiota and Intestinal Mucosal Barrier
Red Sage 📋✍⛔38356496Protective effect of Danshensu against neurotoxicity induced by monosodium glutamate in adult mice and their offspring
Strawberry 📋✍⛔38094291Immunostimulatory and anti-inflammatory impact of Fragaria ananassa methanol extract in a rat model of cadmium chloride-induced pulmonary toxicity
Urolithins 📋 38587058Urolithin A attenuates bupivacaine-induced neurotoxicity in SH-SY5Y cells by regulating the SIRT1-activated PI3K/AKT pathway
Vitamin B3 📋✍⛔37589322Effects of pharmacological doses of niacin on subacute glucocorticoid-induced testicular damage in rats
Vitamin B6 📋✍⛔37701944Protective effect of vitamin B6 against doxorubicin-induced cardiotoxicity by modulating NHE1 expression
Acacetin 📋 36087706Copper sulfate induced toxicological impact on in-vivo zebrafish larval model protected due to acacetin via anti-inflammatory and glutathione redox mechanism
Anise 📋✍⛔37755735Mechanistic Assessment of Anise Seeds and Clove Buds against the Neurotoxicity Caused by Metronidazole in Rats: Possible Role of Antioxidants, Neurotransmitters, and Cytokines
Apple Polyphenols 📋 ⛔37571225Red-Fleshed Apple Flavonoids Extract Alleviates Male Reproductive Injury Caused by Busulfan in Mice
Arjuna 📋✍⛔33816618Antihyaluronidase and Alkaline Phosphatase (ALP) Activities of Medicinal Plants to Combat Echis carinatus Venom-Induced Toxicities
Black Tea Polyphenols 📋 37033331Black Tea Extract, via Modulation of TGF-β Pathway, Prevents Inorganic Arsenic-induced Development of Squamous Cell Carcinoma of the Skin in Swiss Albino Mice
Blackberry 📋 ⛔31040041Blackberry juice anthocyanidins limit cisplatin-induced renal pathophysiology in mice
Catalpol 📋 37778994Catalpol Inhibits Autophagy to Ameliorate Doxorubicin-Induced Cardiotoxicity via the AKT-mTOR Pathway
Choline 📋✍⛔36225707Neurophysiological correlates of memory change in children with fetal alcohol spectrum disorders treated with choline
Chrysanthemum 📋✍⛔35355712An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice
Clove Essential Oil 📋 ⛔36928838Repellent Screening of Selected Plant Essential Oils Against Dengue Fever Mosquitoes Using Behavior Bioassays
D-Limonene 📋✍⛔37773484D-Limonene Alleviates Oxidative Stress Injury of the Testis Induced by Arsenic in Rat
Diallyl Sulfide 📋 36052584[The protective effects of diallyl sulfide (DAS) on genotoxicity induced by benzene]
Escin 📋✍⛔38016364β-escin activates ALDH and prevents cigarette smoke-induced cell death
Geniposide 📋 38508092Geniposide reduced oxidative stress-induced apoptosis in HK-2 cell through PI3K/AKT3/FOXO1 by m6A modification
Hawthorn 📋✍⛔36880395Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis
Honey 📋✍⛔38410096Effect of Honey and Aqueous Garlic Extracts against Short-Term Exposure of Cigarette Tobacco Smoking in Mice: Histopathological and Biochemical Investigations
Liquiritigenin 📋 35744945Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function
Spikenard 📋✍⛔33203171Effect of Nardostachys jatamansi DC. on Apoptosis, Inflammation and Oxidative Stress Induced by Doxorubicin in Wistar Rats
Telmisartan 📋 ⛔37894791Nicotine Impairs the Anti-Contractile Function of Perivascular Adipose Tissue by Inhibiting the PPARγ-Adiponectin-AdipoR1 Axis
Thyme 📋✍⛔35228189Cardioprotective potential of Thymus linearis Benth
UDCA 📋✍⛔38395998Ameliorative effect and mechanism of ursodeoxycholic acid on hydrogen peroxide-induced hepatocyte injury
Ursolic Acid 📋✍⛔38466106Triterpenoid ursolic acid regulates the environmental carcinogen benzo[a]pyrene-driven epigenetic and metabolic alterations in SKH-1 hairless mice for skin cancer interception
Vitamin B1 📋✍⛔36256603Metolachlor Poisoning with Lactic Acidosis Improved by Thiamine Administration: A Case Report
Vitamin B2 📋✍⛔38475697Riboflavin Attenuates Fluoride-Induced Testicular Injury via Interleukin 17A-Mediated Classical Pyroptosis
Vitexin 📋 35693443Chemoprotective effect of vitexin against cisplatin-induced biochemical, spermatological, steroidogenic, hormonal, apoptotic and histopathological damages in the testes of Sprague-Dawley rats
Almond 📋 ⛔33879438Tree nuts supplementation instigates the oxidative status and improves brain performance in male rats
Anethole 📋 35521510Combinations of plant essential oils and their major compositions inducing mortality and morphological abnormality of Aedes aegypti and Aedes albopictus
Avocado 📋✍⛔37944220Antioxidant activity of Carica papaya & Persea americana fruits against cadmium induced neurotoxicity, nephrotoxicity, and hepatotoxicity in rats with a computational approach
Avocado Oil 📋 ⛔36068645Ameliorative effect of avocado oil against lufenuron induced testicular damage and infertility in male rats
Bacopa Monnieri 📋✍⛔38655144Modulatory potential of Bacopa monnieri against aflatoxin B1 induced biochemical, molecular and histological alterations in rats
Bee Venom 📋✍⛔36921536Apitoxin alleviates methyl mercury-induced peripheral neurotoxicity in male rats by regulating dorsal root ganglia neuronal degeneration and oxidative stress
Boron 📋✍⛔38216793Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol
Broccoli 📋 ⛔37821783The Effectiveness of Time in Treatment with Vitamin C and Broccoli Extract on Cadmium Poisoning in Mice: Histological Changes of Testicular Tissue and Cell Apoptotic Index
Cashew 📋 ⛔38298047Antagonistic effectiveness of Anacardium occidentale leaf extract on lead-acetate exposure-induced hepatorenal toxicity in rats
Citronella Essential Oil 📋✍⛔36223259Alternatives to Pyrethroid Resistance: Combinations of Cymbopogon nardus and Ocimum americanum Essential Oils Improve the Bioefficiency Control Against the Adults' Populations of Aedes aegypti (Diptera: Culicidae)
Cornus 📋 38278375Cornus officinalis var. koreana Kitam extracts alleviate cadmium-induced renal fibrosis by targeting matrix metallopeptidase 9
Cranberry 📋✍⛔37823158The role of alcohol extract of cranberry in improving serum indices of experimental metaproterenol-induced heart damage in rats
Cyanidin 📋✍ 38705400Cyanidin improves spatial memory and cognition in bisphenol A-induced rat model of Alzheimer's-like neuropathology by restoring canonical Wnt signaling
Diallyl Disulfide 📋 34214692Diallyl disulfide prevents cigarette smoke-induced emphysema in mice
Diallyl Trisulfide 📋 38276538The Garlic Compound, Diallyl Trisulfide, Attenuates Benzo[a]Pyrene-Induced Precancerous Effect through Its Antioxidant Effect, AhR Inhibition, and Increased DNA Repair in Human Breast Epithelial Cells
Dioscin 📋 38672439Protective Role of Dioscin against Doxorubicin-Induced Chronic Cardiotoxicity: Insights from Nrf2-GPX4 Axis-Mediated Cardiac Ferroptosis
Eucalyptol 📋 38115227Eucalyptol regulates Nrf2 and NF-kB signaling and alleviates gentamicin-induced kidney injury in rats by downregulating oxidative stress, oxidative DNA damage, inflammation, and apoptosis
Ganoderic Acid 📋 38322557Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning
Kiwifruit 📋✍⛔36814509Effects of kiwi fruit ( Actinidia chinensis) polysaccharides on metabolites and gut microbiota of acrylamide-induced mice
Magnolia 📋✍⛔37375908Magnolin Inhibits Paclitaxel-Induced Cold Allodynia and ERK1/2 Activation in Mice
Modified Citrus Pectin 📋✍⛔38522819Effect of modified citrus pectin on galectin-3 inhibition in cisplatin-induced cardiac and renal toxicity
Mucuna Pruriens 📋✍⛔36855363Ameliorating effect of Mucuna pruriens seed extract on sodium arsenite-induced testicular toxicity and hepato-renal histopathology in rats
Neem 📋✍ 38243572Antioxidant and Chemopreventive Effects of Azadirachta indica on Lead Acetate-induced Hepatotoxicity in Male Wistar Rats
Neem Oil 📋✍⛔37151484Formulation of Neem Leaf and Croton Seed Essential Oils as a Natural Insecticide Tested on Mosquitoes and Cockroaches
Nicotinamide 📋✍⛔38087034Hepatoprotective Effect of Nicotinamide Versus Lead-Motivated Hepatotoxicity in Rats via Correcting Effect on Nuclear Factor-kβ Pathway and Glutathione Metabolism
Nutmeg 📋✍⛔35497187Excito-repellency of Myristica fragrans Houtt. and Curcuma longa L. extracts from Southern Thailand against Aedes aegypti (L.)
Persimmon 📋 ⛔35717470Polyphenols from persimmon fruit attenuate acetaldehyde-induced DNA double-strand breaks by scavenging acetaldehyde
PQQ 📋✍⛔38613355Pyrroloquinoline quinone ameliorates PM2.5-induced pulmonary fibrosis through targeting epithelial-mesenchymal transition
Probiotics 📋✍⛔38171106Mixed probiotics modulated gut microbiota to improve spermatogenesis in bisphenol A-exposed male mice
Pumpkin Seed 📋✍⛔38370896The antioxidant role of pumpkin ( Cucurbita pepo) seed extract against acute reproductive toxicity by uranyl acetate in male rats
Rosemary Essential Oil 📋✍⛔36640564Rosemary (Rosmarinus officinalis L.) essential oil alleviates testis failure induced by Etoposide in male rats
Sage Essential Oil 📋 ⛔34275073Bioactive phytochemicals from Salvia officinalis attenuate cadmium-induced oxidative damage and genotoxicity in rats
Shogaol 📋 37795887Preventive Effect of 6-shogaol on D-galactosamine Induced Hepatotoxicity Through NF-?B/MAPK Signaling Pathway in Rats
St. Johns Wort 📋✍⛔33280440Investigation into the protective effects of Hypericum Triquetrifolium Turra seed against cyclophosphamide-induced testicular injury in Sprague Dawley rats
Tamarind 📋 ⛔36926661Hepatoprotective potential of Tamarindus indica following prenatal aluminum exposure in Wistar rat pups
Tea Polyphenols 📋 36643417Protective Effect of Tea Saponins on Alcohol-Induced Gastric Mucosal Injury in Mice
Tetrahydrocurcumin 📋✍ 30401411Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis
Trehalose 📋 ⛔37393413A neuroprotective dose of trehalose is harmless to metabolic organs: comprehensive histopathological analysis of liver, pancreas, and kidney
Arctigenin 📋 36119774Arctigenin attenuates paraquat-induced human lung epithelial A549 cell injury by suppressing ROS/p38 mitogen-activated protein kinases-mediated apoptosis
Asparagus 📋 ⛔37837591Renal-protective effect of Asparagus officinalis aqueous extract against lead-induced nephrotoxicity mouse model
Basil Essential Oil 📋✍⛔36223259Alternatives to Pyrethroid Resistance: Combinations of Cymbopogon nardus and Ocimum americanum Essential Oils Improve the Bioefficiency Control Against the Adults' Populations of Aedes aegypti (Diptera: Culicidae)
Beta-Carotene 📋✍⛔38279214β-Carotene Supplementation Improves Pancreas Function during Moderate Ethanol Consumption: Initial Characterization from a Morphological Overview
Beta-Sitosterol 📋✍⛔37115449Combined β-sitosterol and trimetazidine mitigate potassium dichromate-induced cardiotoxicity in rats through the interplay between NF-κB/AMPK/mTOR/TLR4 and HO-1/NADPH signaling pathways
Bitter Melon 📋✍⛔38027700The neuroprotective potential of turmeric rhizome and bitter melon on aspartame-induced spatial memory impairment in rats
Camellia 📋 ⛔34086174Camellia japonica diminishes acetaminophen-induced acute liver failure by attenuating oxidative stress in mice
Cat's Claw 📋✍⛔29442306Protective effect of Uncaria tomentosa extract against oxidative stress and genotoxicity induced by glyphosate-Roundup® using zebrafish (Danio rerio) as a model
Chamomile 📋✍⛔32509999Hepatoprotective effect of Matricaria chamomilla aqueous extract against 1,2-Dimethylhydrazine-induced carcinogenic hepatic damage in mice
Fluted Gourd 📋 36056790Fluted pumpkin seeds protect the spermatogenesis score index and testicular histology of caffeine treated rats
Fo-Ti Root 📋✍⛔32640539Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2- O-β-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells
Ginger Essential Oil 📋✍ 38298688Ginger volatile oil inhibits the growth of MDA-MB-231 in the bisphenol A environment by altering gut microbial diversity
Glycyrrhetinic Acid 📋 3743649118β-glycyrrhetinic acid ameliorates MPTP-induced neurotoxicity in mice through activation of microglial anti-inflammatory phenotype
Guava 📋 ⛔34817355Assessment of renal and hepato-protective potential of guava leaves in male Sprague dawley rats
Limonin 📋 37832403Limonin ameliorates cisplatin-induced acute liver injury by inhibiting 11β-hydroxysteroid dehydrogenase type 1
Long Pepper 📋 ⛔36969834Amelioration of cyclophosphamide-induced DNA damage, oxidative stress, and hepato- and neurotoxicity by Piper longum extract in rats: The role of γH2AX and 8-OHdG
Loquat 📋✍⛔37498560Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice: in vivo study and in silico prediction of possible mechanisms involving identified polyphenols and/or their circulating metabolites
Magnolol 📋 38729444Magnolol ameliorates fumonisin B1-induced oxidative damage and lipid metabolism dysfunction in astrocyte-like C6 cells
Milk Thistle 📋✍⛔36766219Restoring Activity of Milk Thistle ( Silybum marianum L.) on Serum Biochemical Parameters, Oxidative Status, Immunity, and Performance in Poultry and Other Animal Species, Poisoned by Mycotoxins: A Review
Oleanolic Acid 📋 38668524Oleanolic Acid Acetate Alleviates Cisplatin-Induced Nephrotoxicity via Inhibition of Apoptosis and Necroptosis In Vitro and In Vivo
Parthenolide 📋 37992573Parthenolide alleviates cognitive dysfunction and neurotoxicity via regulation of AMPK/GSK3β(Ser9)/Nrf2 signaling pathway
Peony 📋 ⛔38599475Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway
Quercitrin 📋 34025394Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity
Rapamycin 📋✍ 38365117Rapamycin protects Sertoli cells against BPA-induced autophagy disorders
Rhodiola 📋✍⛔37888707Exploration of Tilmicosin Cardiotoxicity in Rats and the Protecting Role of the Rhodiola rosea Extract: Potential Roles of Cytokines, Antioxidant, Apoptotic, and Anti-Fibrotic Pathways
Theaflavins 📋✍ 37433353The inhibitory effect and mechanism of theaflavins on fluoride transport and uptake in HIEC-6 cell model
Whey Protein 📋✍⛔36950976Whey Protein Concentrate Ameliorates the Methotrexate-Induced Liver and Kidney Damage
Wormwood Essential Oil 📋 ⛔37347548Hepatoprotective effect of Artemisia Argyi essential oil on bisphenol A-induced hepatotoxicity via inhibition of ferroptosis in mice
Aloin 📋 34769051The Intervention and Mechanism of Action for Aloin against Subchronic Aflatoxin B1 Induced Hepatic Injury in Rats
Antioxidants 📋 ⛔36915477Antioxidants prevent particulate matter-induced senescence of lung fibroblasts
Aspirin 📋 ⛔37364758Aspirin ameliorates the neurotoxicity of benzo[a]pyrene in mice and HT22 cells: Possible role of miRNA-mRNA network
Banana 📋 ⛔37031872Musa spp. cultivars as a neutralising source against some toxic activities of Bothrops and Crotalus genus snake venoms
Bergamot 📋✍⛔34944613Cadmium-Induced Kidney Injury in Mice Is Counteracted by a Flavonoid-Rich Extract of Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, via the Enhancement of Different Defense Mechanisms
Beta-Cryptoxanthin 📋 36771049β-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice
Beta-Glucan 📋✍⛔38444353β-Glucan ameliorates cisplatin-induced oxidative and histological damage in kidney and liver of rats
Bilberry 📋✍⛔27714928Bilberry: Chemical Profiling, in Vitro and in Vivo Antioxidant Activity and Nephroprotective Effect against Gentamicin Toxicity in Rats
Celery 📋 ⛔38516746Ameliorating Effect of Apium graveolens (Celery) Extracts on IL-6 Plasma Level and Expression of Caspase 3 on Liver in Animal Model of Lead Intoxication
Cinnamaldehyde 📋 37839279Cytoprotective effects of cinnamaldehyde and adipoRon against cyclophosphamide-induced cardio-renal toxicity in rats: Insights into oxidative stress, inflammation, and apoptosis
Cordycepin 📋 38219840Neuroprotective effects of cordycepin inhibit glutamate-induced apoptosis in hippocampal neurons
Corn Silk 📋✍⛔37579272Protective effect of aqueous and methanolic extracts of corn silk on nicotine-induced reproductive system disorders in male mice
Costus 📋✍⛔35691462Root extracts of Saussurea costus as prospective detoxifying food additive against sodium nitrite toxicity in male rats
Echinacoside 📋 38125366Echinacoside ameliorates doxorubicin‑induced cardiac injury by regulating GPX4 inhibition‑induced ferroptosis
Eclipta Alba 📋✍ 34949157The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats
Eicosapentaenoic Acid 📋✍⛔37450014Mechanistic aspects of ameliorative effects of Eicosapentanoic acid ethyl ester on methotrexate-evoked testiculopathy in rats
Elderberry 📋✍⛔36127818An elderberry-supplemented diet improves spermatogenesis in mice with busulfan-induced azoospermia
Eucalyptus 📋✍⛔34258465Field efficacy of ethnomedicinal plant smoke repellency against Anopheles arabiensis and Aedes aegypti
Eucalyptus Essential Oil 📋 ⛔34917538Repellent Efficacy of Eucalyptus globulus and Syzygium aromaticum Essential Oils against Malaria Vector, Anopheles stephensi (Diptera: Culicidae)
Fennel 📋✍⛔36829884Nephroprotective Effect of Fennel ( Foeniculum vulgare) Seeds and Their Sprouts on CCl4-Induced Nephrotoxicity and Oxidative Stress in Rats
Flaxseed 📋✍⛔35621631Comparing Flaxseed and Perindopril in the Prevention of Doxorubicin and Trastuzumab-Induced Cardiotoxicity in C57Bl/6 Mice
Flaxseed Oil 📋✍⛔38268782Alleviation of carbendazim toxicity effect by Moringa oleifera oil and Linum usitatissimum L . oil on testes of male rats: Physiological, histological and in silico study
Forskolin 📋✍⛔35512548Forskolin alleviates cisplatin-induced acute renal toxicity in rats
Garlic Oil 📋 ⛔37964042Allium sativum Essential Oil Supplementation Reverses the Hepatic Inflammation, Genotoxicity and Apoptotic Effects in Swiss Albino Mice Intoxicated with the Lead Nitrate
Glabridin 📋 36188236Glabridin Plays Dual Action to Augment the Efficacy and Attenuate the Hepatotoxicity of Methotrexate in Arthritic Rats
Glutathione 📋✍⛔38253037Protective effect of glutathione administration on ovarian function in female rats with cyclophosphamide-induced ovarian damage
Grape Seed Oil 📋 ⛔27085796Hepatoprotective effect of grape seed oil against carbon tetrachloride induced oxidative stress in liver of γ-irradiated rat
Honeysuckle 📋 ⛔37107342Protective Effect of Lonicera japonica on PM2.5-Induced Pulmonary Damage in BALB/c Mice via the TGF-β and NF-κB Pathway
Irisin 📋 37499777Irisin protects against doxorubicin-induced cardiotoxicity by improving AMPK-Nrf2 dependent mitochondrial fusion and strengthening endogenous anti-oxidant defense mechanisms
Jojoba Oil 📋✍⛔33481197Ameliorative effects of jojoba oil on fipronil-induced hepatorenal- and neuro-toxicity: the antioxidant status and apoptotic markers expression in rats
Lemon 📋 ⛔36362997Evaluation of the Cardiovascular Effects of Coriandrum sativum and Citrus limon to Treat Arsenic-Induced Endothelial Damage and Hypertension in Rats
Lupeol 📋 35483487Lupeol inhibits pesticides induced hepatotoxicity via reducing oxidative stress and inflammatory markers in rats
Marjoram Essential Oil 📋 ⛔37273614Potential Mechanisms of Imidacloprid-Induced Neurotoxicity in Adult Rats with Attempts on Protection Using Origanum majorana L. Oil/Extract: In Vivo and In Silico Studies
MSM 📋✍⛔35203043Methylsulfonylmethane protects against ethanol-induced brain injury in mice through the inhibition of oxidative stress, proinflammatory mediators and apoptotic cell death
Myrtle 📋✍⛔32333355Myrtle (Myrtus communis) leaf extract suppresses hepatotoxicity induced by monosodium glutamate and acrylamide through obstructing apoptosis, DNA fragmentation, and cell cycle arrest
Oyster 📋 ⛔36547905Ameliorative Effects of Oyster Protein Hydrolysates on Cadmium-Induced Hepatic Injury in Mice
Parsley 📋 ⛔38614435Protective Effect of Petroselinum Crispum Methanolic Extract against Acrylamide-induced Reproductive Toxicity in Male Rats through NF-ĸB, Kinesin, steroidogenesis Pathways
Pineapple 📋✍⛔32682706Modulatory Activities of Plant Extracts on Jellyfish Cytotoxicity
Pu-erh Tea 📋✍⛔27539359Aflatoxin B1 Can Be Complexed With Oxidised Tea Polyphenols and the Absorption of the Complexed Aflatoxin B1 Is Inhibited in Rats
Retinoic Acid 📋 38612663Retinoic Acid Treatment Mitigates PM2.5-Induced Type 2 Inflammation: Insights into Modulation of Innate Immune Responses
Rosehip 📋✍⛔37959727Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in Hepatocytes
Soy 📋✍⛔35625605Dietary Soy Prevents Alcohol-Mediated Neurocognitive Dysfunction and Associated Impairments in Brain Insulin Pathway Signaling in an Adolescent Rat Model
Spearmint 📋 ⛔31646410Nicotine-induced oxidative stress, testis injury, AChE inhibition and brain damage alleviated by Mentha spicata
Tea 📋 35677547Six Types of Tea Reduce Acute Alcoholism in Mice by Enhancing Ethanol Metabolism, Suppressing Oxidative Stress and Inflammation
Vitamin B Complex 📋 ⛔38413451The Protective Effects of Vitamin B Complex on Diclofenac Sodium-Induced Nephrotoxicity: The Role of NOX4/RhoA/ROCK
Vitamin B8 📋✍⛔37619831Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis
Vitamin K2 mk-7 📋✍ 37477796Vitamin K2 protects against aluminium chloride-mediated neurodegeneration
Watermelon 📋 ⛔34841269Watermelon rind ethanol extract exhibits hepato-renal protection against lead induced-impaired antioxidant defenses in male Wistar rats
Zeaxanthin 📋✍⛔36913015Zearalenone induces the senescence of cardiovascular cells in vitro and in vivo
Apple Vinegar 📋✍⛔33282688The Possible Protective Effect of Apple Cider Vinegar on Mercuric Chloride-Induced Changes on Rat Hepatocytes: Immunohistochemical and Ultrastructure Study
Asiaticoside 📋 33868982Hepatoprotective effect of Centella asiatica 50% ethanol extract against acetaminophen-induced acute liver injury in BALB/c mice
Atractylodes 📋✍⛔35285202[Atractylenolide â…  improves acetaminophen-induced acute liver injury in mice by inhibiting MAPK/NF-κB signaling pathway]
Balloon Flower 📋✍⛔37029546Extract of Platycodon grandiflorum Prevents Doxorubicin-induced Cardiotoxicity in Breast Cancer
Blackcurrant 📋✍⛔36009280Dietary Intervention with Blackcurrant Pomace Protects Rats from Testicular Oxidative Stress Induced by Exposition to Biodiesel Exhaust
Brazil Nut 📋 ⛔38575248Brazil nut consumption reduces DNA damage in overweight type 2 diabetes mellitus patients
Chamomile Essential Oil 📋✍⛔38229887Biochemical characterization of chamomile essential oil: Antioxidant, antibacterial, anticancer and neuroprotective activity and potential treatment for Alzheimer's disease
Chia Seeds 📋 ⛔38255724Evaluation of Salvia hispanica as a Therapeutic Agent against Sodium Arsenic-Induced Testicular Toxicity in a Male Rats Model
Coptis Chinensis 📋 ⛔38599826Protective Effects of Coptis chinensis Rhizome Extract and Its Constituents (Berberine, Coptisine, and Palmatine) against α-Synuclein Neurotoxicity in Dopaminergic SH-SY5Y Cells
DHEA 📋✍⛔33727425Dehydroepiandrosterone protects against acetaminophen-induced liver damage in rats by upregulation of Bcl-2 and activation of sirt signalling
Dihydroartemisinin 📋 38351420Dihydroartemisinin abolishes cisplatin-induced nephrotoxicity in vivo
DIM 📋✍⛔38327044Protective effect of diindolylmethane-enriched dietary cabbage against doxorubicin-induced cardiotoxicity in mice
Diosgenin 📋 35149085Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury
Diosmetin 📋 37413905Fenofibrate and Diosmetin in a rat model of testicular toxicity: New insight on their protective mechanism through PPAR-α/NRF-2/HO-1 signaling pathway
Evening Primrose Oil 📋✍⛔36927382Evening primrose oil attenuates oxidative stress, inflammation, fibrosis, apoptosis, and ultrastructural alterations induced by metanil yellow in the liver of rat: a histological, immunohistochemical, and biochemical study
Fennel Essential Oil 📋✍⛔31893363Protective effects of fennel essential oil against oxidative stress and genotoxicity induced by the insecticide triflumuron in human colon carcinoma cells
Fiber 📋✍⛔37892509Adequate Intake of Dietary Fiber May Relieve the Detrimental Impact of Blood Lead on Dyslipidemia among US Adults: A Study of Data from the National Health and Nutrition Examination Survey Database
Flavonoids 📋 ⛔36067934Flavonoids and stilbenoids as a promising arsenal for the management of chronic arsenic toxicity
Folate 📋✍⛔36458173Effects of folic acid on oxidative damage of kidney in lead-exposed rats
GABA 📋✍⛔38584977GABA Administration Ameliorates the Toxicity of Doxorubicin on CSF and the Brain of Albino Rats
Gardenia 📋 ⛔37634748Gardenia extract protects against intrahepatic cholestasis by regulating bile acid enterohepatic circulation
Giloy 📋✍⛔35848691Pro-apoptotic, anti-metastatic, and anti-telomerase activity of Tinospora cordifolia and its active polysaccharide arabinogalactan during Benzo(a)pyrene-induced lung carcinogenesis
Jujube 📋 ⛔36606101Hepatoprotective Effect of Dried Red Jujube Fruit Extract Against Acetaminophen-Induced Acute Hepatotoxicity
Kudzu Root 📋✍⛔33519945The Protective Effects of Water Extracts of Compound Turmeric Recipe on Acute Alcoholism: An Experimental Research Using a Mouse Model
L-Methionine 📋✍⛔37931136L-methionine protects against nephrotoxicity induced by methotrexate through modulation of redox status and inflammation
Lauric Acid 📋✍ 37908709Effect of Lauric acid against ethanol-induced hepatotoxicity by modulating oxidative stress/apoptosis signalling and HNF4α in Wistar albino rats
Lavender Essential Oil 📋✍⛔30409133Lavandula stoechas essential oils protect against Malathion-induces reproductive disruptions in male mice
Maitake Mushrooms 📋 ⛔36145189Grifola frondosa Extract Containing Bioactive Components Blocks Skin Fibroblastic Inflammation and Cytotoxicity Caused by Endocrine Disrupting Chemical, Bisphenol A
Nuciferine 📋 38006352Nuciferine Protects against Obesity-Induced Nephrotoxicity through Its Hypolipidemic, Anti-Inflammatory, and Antioxidant Effects
Olive 📋✍⛔38392217Protective Potential of a Botanical-Based Supplement Ingredient against the Impact of Environmental Pollution on Cutaneous and Cardiopulmonary Systems: Preclinical Study
Olive Polyphenols 📋 36766766Mercury Chloride Affects Band 3 Protein-Mediated Anionic Transport in Red Blood Cells: Role of Oxidative Stress and Protective Effect of Olive Oil Polyphenols
Peas 📋 ⛔37663799Casein and pea enriched high-protein diet attenuates arsenic provoked apoptosis in testicles of adult rats
Pelargonidin 📋 37728621Pelargonidin alleviates acrolein-induced inflammation in human umbilical vein endothelial cells by reducing COX-2 expression through the NF-κB pathway
Peppermint Essential Oil 📋✍⛔29316974Protective effects of Mentha piperita L. leaf essential oil against CCl 4 induced hepatic oxidative damage and renal failure in rats
Perilla 📋✍ 38449453Effects of Perilla frutescens Var. Acuta in Busulfan-Induced Spermatogenesis Dysfunction Mouse Model
Polyphenols 📋 37998340Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy
Progesterone 📋✍⛔37247723CISPLATIN AND PROGESTERONE SEPARATE AND COMBINED ACTION ON RAT BRAIN NUCLEAR PHOSPHOLIPIDS CONTENT
Pumpkin Seed Oil 📋✍⛔38234695Ameliorative Potential of Pumpkin Seed Oil ( Cucurbita pepo L.) Against Tramadol-Induced Oxidative Stress
Raspberry 📋✍⛔36837826Dietary Administration of Black Raspberries and Arsenic Exposure: Changes in the Gut Microbiota and Its Functional Metabolites
Shiitake Mushrooms 📋✍⛔32878044Suppressive Effect of Shiitake Extract on Plasma Ethanol Elevation
Shilajit 📋✍⛔29947420Profertility effects of Shilajit on cadmium-induced infertility in male mice
Skullcap 📋✍⛔35676380Scutellaria baicalensis and its constituents baicalin and baicalein as antidotes or protective agents against chemical toxicities: a comprehensive review
Soy Isoflavones 📋✍⛔36290760Soy Isoflavones Protect Neuronal PC12 Cells against Hypoxic Damage through Nrf2 Activation and Suppression of p38 MAPK and AKT-mTOR Pathways
Trans-Resveratrol 📋 36008536Toxicity mechanisms of aflatoxin M 1 assisted with molecular docking and the toxicity-limiting role of trans-resveratrol
Yam 📋 34426927Dioscorea deltoidea Leaf Extract (DDLE) Attenuates Cisplatin-Induced Ovarian Injury via Regulation of Oxidative Stress
Yiang Yiang Essential Oil 📋 ⛔31965826Insecticidal activity of two essential oils used in perfumery (ylang ylang and frankincense)
Alpha-Linolenic Acid 📋✍⛔38039041Alpha-linolenic acid protects against methotrexate-induced nephrotoxicity in mouse kidney cells
Apricot Kernels 📋✍⛔32794256Genotoxic and antigenotoxic potential of amygdalin on isolated human lymphocytes by the comet assay
Arctiin 📋 33123566Arctiin Antagonizes Triptolide-Induced Hepatotoxicity via Activation of Nrf2 Pathway
Artemisinin 📋 37089824Comparative assessment of hepatoprotective properties of Artesunate and flavonoids from Artemisia annua on acetaminophen and carbon tetrachloride-induced cytotoxicity in primary mice hepatocytes
Ashitaba 📋✍⛔28386382Protective effects of an ethanol extract of Angelica keiskei against acetaminophen-induced hepatotoxicity in HepG2 and HepaRG cells
Astragalin 📋 33916310Astragalin Inhibits Cigarette Smoke-Induced Pulmonary Thrombosis and Alveolar Inflammation and Disrupts PAR Activation and Oxidative Stress-Responsive MAPK-Signaling
Azadirachtin 📋 38001854Azadirachtin Attenuates Carcinogen Benzo(a) Pyrene-Induced DNA Damage, Cell Cycle Arrest, Apoptosis, Inflammatory, Metabolic, and Oxidative Stress in HepG2 Cells
Bee Pollen 📋✍⛔35589738Protective effect of bee pollen in acute kidney injury, proteinuria, and crystalluria induced by ethylene glycol ingestion in rats
Beta-Lapachone 📋 37867446β-lapachone protects against doxorubicin-induced hepatotoxicity through modulation of NAD+ /SIRT-1/FXR/p-AMPK/NF-kB and Nrf2 signaling axis
Brussels Sprouts 📋 ⛔36642108Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts
Calcium 📋✍⛔33629228Dietary Calcium Alleviates Fluorine-Induced Liver Injury in Rats by Mitochondrial Apoptosis Pathway
Calcium D-Glucarate 📋✍⛔36771439Mechanistic Understanding of D-Glucaric Acid to Support Liver Detoxification Essential to Muscle Health Using a Computational Systems Biology Approach
Cardamonin 📋 35697027Dual effects of cardamonin/alpinetin and their acrolein adducts on scavenging acrolein and the anti-bacterial activity from Alpinia katsumadai Hayata as a spice in roasted meat
Carotenoids 📋✍⛔22465157Carotenoids and DNA damage
Casein Protein 📋✍⛔37663799Casein and pea enriched high-protein diet attenuates arsenic provoked apoptosis in testicles of adult rats
Chaga Mushrooms 📋✍⛔34275842Protective effect of Phaeoporus obliquus polysaccharide against acute liver injury induced by carbon tetrachloride and alcohol in mice
Chebulinic Acid 📋 33561764In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit
Cherry 📋 ⛔33805724Tart Cherry Extract Containing Chlorogenic Acid, Quercetin, and Kaempferol Inhibits the Mitochondrial Apoptotic Cell Death Elicited by Airborne PM 10 in Human Epidermal Keratinocytes
Chickpea 📋 ⛔28552514Aluminum-induced Molecular Neurodegeneration: The Protective Role of Genistein and Chickpea Extract
Chicory 📋✍⛔38045213Cichorium intybus L. significantly alleviates cigarette smoke-induced acute lung injury by lowering NF-κB pathway activation and inflammatory mediators
Citrus Fruits 📋 ⛔37850547Citrus peel extract protects against diesel exhaust particle-induced chronic obstructive pulmonary disease-like lung lesions and oxidative stress
Conjugated Linoleic Acid 📋✍⛔36545457Effect of Conjugated Linoleic Acid (CLA) Supplementation on Expression of B-Cell Lymphoma-2 (Bcl-2) in the Bladder Epithelium of Wistar (Rattus norvegicus) Rats Exposed to Cigarette Smoke
Coriander Essential Oil 📋✍⛔30932786Hepatoprotective Activity of Linalool in Rats Against Liver Injury Induced by Carbon Tetrachloride
Fish Collagen 📋✍⛔35447905Fish Collagen Peptides Protect against Cisplatin-Induced Cytotoxicity and Oxidative Injury by Inhibiting MAPK Signaling Pathways in Mouse Thymic Epithelial Cells
Food 📋 35439354Diet impacts triple-negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin-mediated cardiac dysfunction
Frankincense Essential Oil 📋 ⛔31965826Insecticidal activity of two essential oils used in perfumery (ylang ylang and frankincense)
Glycine 📋✍⛔38636261The use of amino acids and their derivates to mitigate against pesticide-induced toxicity
Guggul 📋✍⛔34560545Myrrhanone B and Myrrhanol B from resin of Commipohora mukul exhibit hepatoprotective effects in-vivo
Hazelnut 📋 ⛔34664725Effects of hazelnut supplemented diet on doxorubicin-induced damage of reproductive system in male rats
Horny Goat Weed 📋✍⛔32256652Epimedium Polysaccharide Ameliorates Benzene-Induced Aplastic Anemia in Mice
Hyaluronic Acid 📋✍⛔33114764Conjugation with Methylsulfonylmethane Improves Hyaluronic Acid Anti-Inflammatory Activity in a Hydrogen Peroxide-Exposed Tenocyte Culture In Vitro Model
Iodine 📋✍⛔33507599Lithium from breast-milk inhibits thyroid iodine uptake and hormone production, which are remedied by maternal iodine supplementation
Isoflavones 📋✍⛔34197824DEHP-induced testicular injury through gene methylation pathway and the protective effect of soybean isoflavones in Sprague-Dawley rats
Isoquercitrin 📋 33918248Synergistic Protection by Isoquercitrin and Quercetin against Glutamate-Induced Oxidative Cell Death in HT22 Cells via Activating Nrf2 and HO-1 Signaling Pathway: Neuroprotective Principles and Mechanisms of Dendropanax morbifera Leaves
Jasmine 📋 ⛔36144196Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
Krill Oil 📋✍⛔36185650Antarctic krill ( Euphausia superba) oil modulatory effects on ethanol-induced acute injury of the gastric mucosa in rats
L-Leucine 📋✍⛔38165500Cardioprotective Effects of Leucine Supplementation against Doxorubicin-Induced Cardiotoxicit
L-Threonine 📋✍⛔36615370Threonine Facilitates Cd Excretion by Increasing the Abundance of Gut Escherichia coli in Cd-Exposed Mice
Lecithin 📋✍⛔37676407The Antioxidant and anti-inflammatory Activity of Selenium and Lecithin Combination Against ethanol-induced Gastric Ulcer in mice via Modulating IGF-1/PTEN/Akt/FoxO3a Signaling
Lemon Balm 📋✍⛔36469234Melissa Officinalis L. aqueous extract pretreatment decreases methotrexate-induced hepatotoxicity at lower dose and increases 99mTc-phytate liver uptake, as a probe of liver toxicity assessment, in rats
Lemongrass 📋✍⛔35871196Sodium benzoate induced toxicities in albino male rats: mitigating effects of Ficus carica and Cymbopogon citratus leave extract
Lentil 📋 ⛔36438775Antioxidative potential and ameliorative effects of green lentil ( Lens culinaris M.) sprouts against CCl4-induced oxidative stress in rats
Ligustilide 📋 33111362Ligustilide alleviates neurotoxicity in SH-SY5Y cells induced by Aβ25-35 via regulating endoplasmic reticulum stress and autophagy
Liquiritin 📋 37160483Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11/GPX4 pathway
Maca Root 📋✍⛔38518815A novel approach of using Maca root as a radioprotector in a rat testicular damage model focusing on GRP78/CHOP/Caspase-3 pathway
Mandarin 📋 38350206Citrus reticulata peel extract mitigates oxidative stress and liver injury induced by abamectin in rats
Marigold 📋✍⛔26513373Total antioxidant and oxidant status of plasma and renal tissue of cisplatin-induced nephrotoxic rats: protection by floral extracts of Calendula officinalis Linn
Myrrh 📋✍⛔34829707Commiphora myrrh Supplementation Protects and Cures Ethanol-Induced Oxidative Alterations of Gastric Ulceration in Rats
Nattokinase 📋✍⛔35648353Nattokinase attenuates bisphenol A or gamma irradiation-mediated hepatic and neural toxicity by activation of Nrf2 and suppression of inflammatory mediators in rats
Neferine 📋 36326941Neferine mitigates cisplatin-induced acute kidney injury in mice by regulating autophagy and apoptosis
Nimbolide 📋 35143824Co-treatment of Nimbolide augmented the anti-arthritic effects of methotrexate while protecting against organ toxicities
Omega-6 Fatty Acids 📋✍⛔38585532Evaluating the renoprotective effects of omega-3-6-9 against cisplatin-induced nephrotoxicity in mice
Oregano Essential Oil 📋✍⛔38613208Therapeutic benefit of oregano oil in the acute idiosyncratic hepatotoxicity induced by carbon tetrachloride in rats: Adverse effects of high dose of oreganum
Pau d'Arco 📋✍⛔38705428LC-qTOF-MS/MS phytochemical profiling of Tabebuia impetiginosa (Mart. Ex DC.) Standl. leaf and assessment of its neuroprotective potential in rats
Peach 📋 ⛔28382283Protective Effect of White-fleshed Peach ( Prunus persica (L.) Batsch) on Chronic Nicotine-induced Toxicity
Phosphatidylcholine 📋✍⛔32640840Critical Importance of Dietary Methionine and Choline in the Maintenance of Lung Homeostasis During Normal and Cigarette Smoke Exposure Conditions
Phosphatidylserine 📋✍⛔37666289Investigation of the potential ameliorative effects of DHA-enriched phosphatidylserine on bisphenol A-induced murine nephrotoxicity
Phytoestrogens 📋 ⛔32963737Phytoestrogens by inhibiting the non-classical oestrogen receptor, overcome the adverse effect of bisphenol A on hFOB 1.19 cells
Pistachio 📋✍⛔36856595Cardioprotective Effect of Pistacia vera L. (Green Pistachio) Hull Extract in Wistar Albino Rats with Doxorubicin-Induced Cardiac Damage
Polypodium Leucotomos 📋✍⛔36358556Protective Effect of the Hydrophilic Extract of Polypodium leucotomos, Fernblock®, against the Synergistic Action of UVA Radiation and Benzo[a]pyrene Pollutant
Pomelo 📋 ⛔23401708Pummelo protects Doxorubicin-induced cardiac cell death by reducing oxidative stress, modifying glutathione transferase expression, and preventing cellular senescence
Prebiotics 📋✍⛔38445787Prebiotics counteract the morphological and functional changes secondary to chronic cisplatin exposition in the proximal colon of mice
Pregnenolone 📋✍⛔37259756Pregnenolone protects the liver against doxorubicin-induced cellular injury by anti-inflammatory, antioxidant, and antiapoptotic mechanisms: role of Keap1/Nrf2/HO-1 and P-glycoprotein
Proanthocyanidins 📋 38088309The effects of proanthocyanidin on testicular toxicity in rats exposed to a glyphosate-based herbicide
Prunella Vulgaris 📋✍⛔37640280An aqueous extract of Prunella vulgaris L. ameliorates cadmium-induced bone loss by promoting osteogenic differentiation in female rats
Quinoa 📋 ⛔36066553The protective effect of quinoa on the gastric mucosal injury induced by absolute ethanol
Red Yeast Rice 📋✍⛔33726520[Doctor, Do You Know Red Yeast Rice?]
Rice 📋 ⛔36000692Antioxidant extract of black rice prevents renal dysfunction and renal fibrosis caused by ethanol-induced toxicity
Rose 📋 38089182Neuroprotective Effects of Rosa damascena Extract against Aluminum Chloride-Induced Brain Damage in Rat Offspring
Safranal 📋 38484848Improvement of inhaled paraquat induced lung and systemic inflammation, oxidative stress and memory changes by safranal
SAMe 📋✍⛔36310362The Relationship between Prohibitin 1 Expression, Hepatotoxicity Induced by Acetaminophen, and Hepatoprotection by S-Adenosylmethionine in AML12 Cells
Scutellarein 📋 38516760Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress
Seaweeds 📋 ⛔36977879Seaweed Sargassum aquifolium extract ameliorates cardiotoxicity induced by doxorubicin in rats
Spermidine 📋 37741320Spermidine suppresses oxidative stress and ferroptosis by Nrf2/HO-1/GPX4 and Akt/FHC/ACSL4 pathway to alleviate ovarian damage
Spices 📋 35245798Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity
Star Fuit 📋 ⛔35359233Star fruit extract and C-glycosylated flavonoid components have potential to prevent air pollutant-induced skin inflammation and premature aging
Stigmasterol 📋 36898255Stigmasterol isolated from Azadirachta indica flowers attenuated glutamate-induced neurotoxicity via downregulation of the Cdk5/p35/p25 signaling pathway in the HT-22 cells
Sweet Potato 📋 ⛔34438266Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice
Thyme Essential Oil 📋 ⛔33652584Protective Effect of Thymus serrulatus Essential Oil on Cadmium-Induced Nephrotoxicity in Rats, through Suppression of Oxidative Stress and Downregulation of NF-κB, iNOS, and Smad2 mRNA Expression
Tongkat Ali 📋✍⛔31214269Nephroprotective Effect of Herbal Extract Eurycoma longifolia on Paracetamol-Induced Nephrotoxicity in Rats
Valerian Root 📋✍⛔34066673Ameliorative Effects of the Sesquiterpenoid Valerenic Acid on Oxidative Stress Induced in HepG2 Cells after Exposure to the Fungicide Benomyl
Vitamin A 📋✍⛔35685889Insight Into Biological Targets and Molecular Mechanisms in the Treatment of Arsenic-Related Dermatitis With Vitamin A via Integrated in silico Approach
Vitamins 📋 37834378Melatonin and Vitamins as Protectors against the Reproductive Toxicity of Bisphenols: Which Is the Most Effective? A Systematic Review and Meta-Analysis
Witch Hazel 📋✍⛔12711142Genotoxic and antigenotoxic effects of catechin and tannins from the bark of Hamamelis virginiana L. in metabolically competent, human hepatoma cells (Hep G2) using single cell gel electrophoresis
Withaferin A 📋 37426503Antitumor activity of withaferin-A and propolis in benz (a) pyrene-induced breast cancer
Yerba Mate 📋✍⛔37219520Beneficial effects of mate-herb, Ilex paraguariensis St. Hil. against potassium dichromate-induced oxidative stress and nephrotoxicity
5-HTP 📋✍⛔384626935-Hydroxytryptophan acts as a gap junction inhibitor to limit the spread of chemotherapy-induced cardiomyocyte injury and mitochondrial dysfunction
Activated Charcoal 📋✍⛔34845647Activated Charcoal and Bicarbonate for Aspirin Toxicity: a Retrospective Series
Almond Oil 📋 ⛔32210674Therapeutic influences of almond oil on male rats exposed to a sublethal concentration of lead
Aloe-Emodin 📋 37364691Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis
Arachidonic Acid 📋✍⛔35065163Therapeutic role of eicosapentaenoic and arachidonic acid in benzo(a) pyrene-induced toxicity in HUVEC endothelial cells
Bergamot Essential Oil 📋✍⛔32971212Bergamot essential oil attenuate aluminum-induced anxiety-like behavior through antioxidation, anti-inflammatory and GABA regulation in rats
Berries 📋 19003579Prevention of oxidative DNA damage by bioactive berry components
Beta-Alanine 📋✍⛔17086479Effect of Beta-Alanine Administration on Carbon Tetrachloride-Induced Acute Hepatotoxicity
Black Cohosh 📋✍⛔36611626Protective Effect of Cimicifuga racemosa (L.) Nutt Extract on Oocyte and Follicle Toxicity Induced by Doxorubicin during In Vitro Culture of Mice Ovaries
Black Pepper 📋✍⛔27396401Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine
Bladderwrack 📋✍⛔33466689In Vitro Chemopreventive Potential of Phlorotannins-Rich Extract from Brown Algae by Inhibition of Benzo[a]pyrene-Induced P2X7 Activation and Toxic Effects
Buckwheat 📋 ⛔34763933Buckwheat-enriched diet alleviates bisphenol A mediated oxidative stress via modulation of sirtuin 1 and antioxidant status in experimental rats
Camphor 📋✍⛔37175177The Mosquito Larvicidal Activity of Lignans from Branches of Cinnamomum camphora chvar. Borneol
Cannabidiol Oil 📋✍⛔37971510Prospective affirmative therapeutics of cannabidiol oil mitigates doxorubicin-induced abnormalities in kidney function, inflammation, and renal tissue changes
Cantaloupe 📋 ⛔38348351Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics and in silico electrophysiological models
Caraway 📋 ⛔36284942Effect of Caraway Seed Extract on the Blood Biochemistry and Antioxidant Capacity among the Hyperoxidative Stress-Induced Rats
Caraway Essential Oil 📋 ⛔20608729Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae)
Carnosol 📋 29476131The Mechanisms of Carnosol in Chemoprevention of Ultraviolet B-Light-Induced Non-Melanoma Skin Cancer Formation
Castor Oil 📋✍⛔38696683Methanolic Extract of Ricinus Communis ameliorated cardiovascular dysfunction in dichlorvos-exposed rats
Citral 📋 31687359Insecticidal activities of Citrus aurantifolia essential oil against Aedes aegypti (Diptera: Culicidae)
Colostrum 📋✍⛔37189633Colostrum and Lactoferrin Protect against Side Effects of Therapy with Antibiotics, Anti-inflammatory Drugs and Steroids, and Psychophysical Stress: A Comprehensive Review
Creatine 📋✍⛔33374297Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence
Cryptotanshinone 📋 37399718Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis
Cumin 📋 ⛔29947676Essential Oils of Green Cumin and Chamomile Partially Protect Against Acute Acetaminophen Hepatotoxicity in Rats
Delphinidin 📋 36429167Metabolic Regulation Effect and Potential Metabolic Biomarkers of Pre-Treated Delphinidin on Oxidative Damage Induced by Paraquat in A549 Cells
Deodar Cedar 📋 35325515Attenuation of cisplatin induced myelosuppression by methanol extract of Cedrus deodara in wistar rats
Eleuthero 📋✍⛔38380572Integrating serum pharmacochemistry and network pharmacology to explore the molecular mechanisms of Acanthopanax senticosus (Rupr. & Maxim.) Harms on attenuating doxorubicin-induced myocardial injury
Essential Amino Acids 📋✍⛔37242170Essential Amino Acids-Rich Diet Increases Cardiomyocytes Protection in Doxorubicin-Treated Mice
Eucommia 📋✍⛔35607702Effect of Ethyl Acetate Fraction from Eucommia ulmoides Leaves on PM 2.5-Induced Inflammation and Cognitive Dysfunction
Gamma-Linolenic Acid 📋✍⛔35740923Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study
Geranium 📋 35489079Protective Effect of the Hydroalcoholic Extract of Pelargonium Graveolens L. on Rats with Acetaminophen- Induced Nephrotoxicity
Ginkgetin 📋 37343436The potential beneficial role of Ginkgetin in doxorubicin-induced hepatotoxicity: Elucidating the underlying claim
Glucosamine 📋✍⛔36462645Protective effect of glucosamine on zearalenone-induced reproductive toxicity and placental dysfunction in mice
Guggulsterone 📋 38609738Guggulsterone protects against cigarette smoke-induced COPD linked lung inflammation
Hypericin 📋 33050761Hypericin, a medicinal compound from St. John's Wort, inhibits genotoxicity induced by mutagenic agents in V79 cells
Icaritin 📋 34147477IGF-1 receptor is involved in the regulatory effects of icariin and icaritin in astrocytes under basal conditions and after an inflammatory challenge
Inulin 📋✍⛔38072026Inulin alleviates perfluorooctanoic acid-induced intestinal injury in mice by modulating the PI3K/AKT/mTOR signaling pathway
Iron 📋✍⛔31729815Effects of combined administration of calcium, iron, zinc, chrysanthemum flavonoids, and DMSA on the treatment of lead intoxication in mice
Jackfruit 📋 ⛔38201995Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice
L-Alanine 📋✍⛔27317126Benefits of L-alanine or L-arginine supplementation against adiposity and glucose intolerance in monosodium glutamate-induced obesity
L-Histidine 📋✍⛔19799668Protective Effects From Carnosine and Histidine on Acetaminophen-Induced Liver Injury
L-Tryptophan 📋✍⛔29978260Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion
Lavender 📋✍⛔31382408Hepatoprotection of Mentha aquatica L., Lavandula dentata L. and Leonurus cardiaca L
Lemon Verbena 📋 ⛔38392217Protective Potential of a Botanical-Based Supplement Ingredient against the Impact of Environmental Pollution on Cutaneous and Cardiopulmonary Systems: Preclinical Study
Lime Essential Oil 📋✍⛔31687359Insecticidal activities of Citrus aurantifolia essential oil against Aedes aegypti (Diptera: Culicidae)
Lion's Mane Mushrooms 📋✍⛔34679002Aflatoxin B1 Toxicity in Zebrafish Larva ( Danio rerio): Protective Role of Hericium erinaceus
Lychee 📋 ⛔30257405The hydroethanolic Litchi chinensis leaf extract alleviate hepatic injury induced by carbon tetrachloride (CCl 4) through inhibition of hepatic inflammation
Matcha Tea 📋 34943034Powdered Green Tea (Matcha) Attenuates the Cognitive Dysfunction via the Regulation of Systemic Inflammation in Chronic PM 2.5-Exposed BALB/c Mice
Minerals 📋 37998340Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy
Mugwort 📋 ⛔35351963Repellency and insecticidal activity of seven Mugwort (Artemisia argyi) essential oils against the malaria vector Anopheles sinensis
Mustard 📋 ⛔37959024The Nephroprotective Potential of Brassica nigra Sprout Hydroalcoholic Extract against Carbon Tetrachloride-Induced Renal Toxicity in Rats
Myrtle Essential Oil 📋✍⛔32842205[To explore the therapeutic effect of myrtle oil, anthocyanin and hyaluronic acid in combination with topical application on allergic rhinitis in rats exposed to PM2.5]
NAD 📋 35983933Nicotinamide adenine dinucleotide attenuates acetaminophen-induced acute liver injury via activation of PARP1, Sirt1, and Nrf2 in mice
Oats 📋 ⛔37439681Short-Term Dietary Intervention with Whole Oats Protects from Antibiotic-Induced Dysbiosis
Oleic Acid 📋 ⛔38456238Anti-pollutant effect of oleic acid against urban particulate matter is mediated via regulation of AhR- and TRPV1-mediated signaling in vitro
Omega-9 Fatty Acids 📋 38585532Evaluating the renoprotective effects of omega-3-6-9 against cisplatin-induced nephrotoxicity in mice
Osmanthus 📋✍⛔30211228Evaluation of the Pharmacokinetics and Hepatoprotective Effects of Phillygenin in Mouse
Oyster Mushrooms 📋 ⛔32428092Nephroprotective Effect of Pleurotus Ostreatus Extract Against Cadmium Chloride Toxicity in Rats
Papain 📋✍⛔27069723Modulatory Potentials of Aqueous Leaf and Unripe Fruit Extracts of Carica Papaya Linn. (Caricaceae) Against Carbon Tetrachloride and Acetaminophen-Induced Hepatotoxicity in Rats
Parsnip 📋 ⛔35016997Apiaceous vegetables protect against acrolein-induced pulmonary injuries through modulating hepatic detoxification and inflammation in C57BL/6 male mice
Patchouli 📋✍⛔37298745Analysis of Essential Oils Components from Aromatic Plants Using Headspace Repellent Method against Aedes aegypti Mosquitoes
PEA 📋✍⛔36551301Palmitoylethanolamide Mitigates Paclitaxel Toxicity in Primary Dorsal Root Ganglion Neurons
Pear 📋 ⛔36856473Effects of Pear Extracts on Microbiome and Immunocytokines to Alleviate Air Pollution-Related Respiratory Hypersensitivity
Pectin 📋✍⛔37285678Pectin alleviates the pulmonary inflammatory response induced by PM2.5 from a pig house by modulating intestinal microbiota
Peppermint 📋✍⛔23011739Mentha piperita as a pivotal neuro-protective agent against gamma irradiation induced DNA fragmentation and apoptosis : Mentha extract as a neuroprotective against gamma irradiation
Piperlongumine 📋 35216124Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
Potassium 📋✍⛔37195612Alleviating air pollutant-associated hypertension by potassium intake in Korean adults: a cross-sectional study from the 2012-2016 Korea National Health and Nutrition Examination Survey
Potato 📋 ⛔21106930Pigmented potato consumption alters oxidative stress and inflammatory damage in men
Prickly Pear 📋 ⛔35214853Opuntia ficus-indica Alleviates Particulate Matter 10 Plus Diesel Exhaust Particles (PM10D)-Induced Airway Inflammation by Suppressing the Expression of Inflammatory Cytokines and Chemokines
Protein 📋✍⛔30201912Walnut Protein Hydrolysates Play a Protective Role on Neurotoxicity Induced by d-Galactose and Aluminum Chloride in Mice
PUFA 📋 36456856Polyunsaturated fatty acids, vitamin E and lycopene alleviate ambient particulate matter organic extracts-induced oxidative stress in canine lung cells via the Nrf2/HO-1 pathway
Pumpkin 📋 ⛔34587668The role of pumpkin pulp extract carotenoids against mycotoxin damage in the blood brain barrier in vitro
Pyridoxal-5-Phosphate 📋✍⛔35678366Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K
Radish 📋 ⛔36501112Hepatoprotective Effects of Radish ( Raphanus sativus L.) on Acetaminophen-Induced Liver Damage via Inhibiting Oxidative Stress and Apoptosis
Rhubarb 📋 ⛔35062061Epigenetic changes in inflammatory genes and the protective effect of cooked rhubarb on pancreatic tissue of rats with chronic alcohol exposure
Rosavin 📋 ⛔36097321Pretreatment with rosavin attenuates PM2.5-induced lung injury in rats through antiferroptosis via PI3K/Akt/Nrf2 signaling pathway
Rye 📋 ⛔34439463Unraveling the Bioactive Profile, Antioxidant and DNA Damage Protection Potential of Rye ( Secale cereale) Flour
Senolytics 📋 38225896Senolytic treatment alleviates doxorubicin-induced chemobrain
Sesame 📋✍⛔35968694Suppression of colonic oxidative stress caused by chronic ethanol administration and attenuation of ethanol-induced colitis and gut leakiness by oral administration of sesaminol in mice
Shea 📋 ⛔33854955Ethanol extract of Vitellaria paradoxa (Gaertn, F) leaves protects against sodium arsenite - induced toxicity in male wistar rats
Sodium Bicarbonate 📋✍⛔34845647Activated Charcoal and Bicarbonate for Aspirin Toxicity: a Retrospective Series
Sorghum 📋 ⛔35523904Apigeninidin-rich Sorghum bicolor (L. Moench) extracts suppress A549 cells proliferation and ameliorate toxicity of aflatoxin B1-mediated liver and kidney derangement in rats
St. Johns Wort Oil 📋 ⛔28101834Management of Acute Skin Toxicity With Hypericum Perforatum and Neem Oil During Platinum-Based Concurrent Chemo-Radiation in Head and Neck Cancer Patients
Star Anise 📋✍⛔35521510Combinations of plant essential oils and their major compositions inducing mortality and morphological abnormality of Aedes aegypti and Aedes albopictus
Sulfur 📋✍⛔24106592Effect of Methylsulfonylmethane Pretreatment on Aceta-minophen Induced Hepatotoxicity in Rats
Sunflower Oil 📋✍⛔37627620Ozonated Sunflower Oil Exerted Potent Anti-Inflammatory Activities with Enhanced Wound Healing and Tissue Regeneration Abilities against Acute Toxicity of Carboxymethyllysine in Zebrafish with Improved Blood Lipid Profile
Tea Polysaccharides 📋 23623843Protective effects of Keemun black tea polysaccharides on acute carbon tetrachloride-caused oxidative hepatotoxicity in mice
Tomato 📋 ⛔22551119Tomato juice intake suppressed serum concentration of 8-oxodG after extensive physical activity
Vegetables 📋 28822504Is smog innocuous? Air pollution and cardiovascular disease
Vitamin B7 📋✍⛔38045419Biotin rescues manganese-induced Parkinson's disease phenotypes and neurotoxicity
Vitamin K 📋✍⛔33634559Statins, vascular calcification, and vitamin K-dependent proteins: Is there a relation?
Vitamin K1 📋✍⛔28717059Pharmacological effects of a vitamin K 1 2,3-epoxide reductase (VKOR) inhibitor, 3-acetyl-5-methyltetronic acid, on cisplatin-induced fibrosis in rats
Vitamin K2 📋✍⛔33805625Molecular Mechanism of Vitamin K2 Protection against Amyloid-β-Induced Cytotoxicity
Vitex 📋✍⛔38152275Evaluation of the therapeutic efficacy of Vitex agnus-castus extract on cisplatin-induced hematotoxicity in female Wistar rats
Watercress 📋✍⛔35247882Use of Freeze-dried Watercress for Detoxification of Carcinogens and Toxicants in Smokers: Implications of the Findings and Potential Opportunities
White Mushrooms 📋 ⛔37421350Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats
Wine 📋 ⛔26710838Green Tea, Red Wine and Lemon Extracts Reduce Experimental Tumor Growth and Cancer Drug Toxicity
Withanolides 📋 35159267Effect of Withanolide A on 7-Ketocholesterol Induced Cytotoxicity in hCMEC/D3 Brain Endothelial Cells
Wood Ear Mushrooms 📋 ⛔34681485Auricularia auricula Melanin Protects against Alcoholic Liver Injury and Modulates Intestinal Microbiota Composition in Mice Exposed to Alcohol Intake